Assessment of Clinico-Pathological Characteristics of Renal Biopsy: Tertiary Care Centre Based Study

Abstract

Introduction: Nephrology's most essential diagnostic tool is the kidney biopsy. The purpose this study is to investigate the clinico-pathological characteristics of individuals having renal biopsies at a tertiary care facility in Mumbai, analyse the renal biopsy histopathological pattern and investigate the incidence and kinds of complications in these individuals.

Objective: This single center cross-sectional observational study was conducted from October 2020 to September 2022 in tertiary level.

Methods: The conventional indication for kidney biopsies was based on clinical presentation and studies. The patient's demographic profile, the reason for the kidney biopsy, and histological patterns were investigated and analysed with the use of relevant statistical methods.

Results: The majority of patients (72%) were less than 60 years old, whereas the greatest number of patients (45%) were between the ages of 20 and 39.The results reflected that men outnumbered women and 76% of the participants had primary renal disease, 21% had secondary renal disease and 3% had normal renal biopsy results. The most prevalent reason for doing a kidney biopsy was incidentally found, unexplained renal failure, followed by oliguria and edoema.

Conclusions: This study demonstrates that glomerular illnesses, accounting for 88% of cases, are significantly more prevalent than disorders of the tubulo-interstitial (7%) and vascular (2%) compartments, 3% of the biopsies had a normal histological pattern.Owing to the small sample size and the research population consisting mostly of serving people, the results of this study cannot be generalised to the general population.