Clinical Evaluation Of Rubrics Of Pulsatilla From Synthesis Repertory To Assess Its Validation By Bayesian Theorem

Abstract

Homoeopathic prescription is done on the Totality of symptoms formed by indicative symptoms and signs of the patients, but knowledge about those symptoms is not organized and controlled. Moreover, there are numerous rubrics and symptoms listed in our Repertories and Materia Medica for specific medicine which are based on their absolute frequency. There are false entries in our repertories due to this absolute occurrence in successful circumstances. To consider a symptom a keynote or characteristic of a specific medicine, the Likelihood Ratio (LR) of that symptom must be higher in the patients exhibiting good therapeutic response to that medicine than in the remaining population. Based on Bayesian statistics, likelihood Ratio (LR) may yield a better estimation of a medicine’s indication than the existing method of entry of symptoms into Materia Medica and Repertories.

An Observational Retrospective study was undertaken to evaluate Rubrics of prominently present symptoms of Pulsatilla by implication of the Likelihood Ratio (LR). 316 cases of prescriptions of Pulsatilla were taken for study and 20 most prominent symptoms of Pulsatilla were selected for the study. Pulsatilla for 1 Rubrics (Company desire for) could be upgraded for BOLD CAPITAL and 1 Rubric (Fullness sensation of, Epigastrium) could be upgraded for bold small typeface, for 4 rubrics (Consolation amelioration, Timidity, Fear-alone being of, Eructations; Type of-sour), the typeface is analogous to the existing typeface in Synthesis Repertory, for others (Weeping-tearful mood, Thirstlessness, Menses-suppressed menses, Eruptions acne, Menses before-aggravation, Heartburn-fat food-after, Head-pain-pulsating, Cough-Dry night at, Warm-agg) rubrics, the typeface could be downgraded but with caution while as 1 rubric (Leukorrhea- cream like) is still doubtful.